Latest Terminology Update

As you are all probably aware CDISC now updates the controlled terminology on a quarterly basis and the latest release came out in late March. I wrote about some of the issues with the terminology when the last release came out but this will just be a short post to point out some of the more important changes

One way of seeing the changes is to look at the change spreadsheets that exist on the NCIt website and then goto to the SDTM and COA directories where you can find the files to download. These are detailed change sheets. The two small issues I have with the sheets is that: a) they are separate and in my day work I see the terminology as one; and b) they don’t have the context of the change, i.e. all the other attributes of the code list or code list item that have not changed nor the context of the whole code list.

This is partly why I developed the simple difference and history tools to allow the changes to be seen in context and as one set (they only hold the SDTM and COA terminologies at present but there is no reason why the CDASH and ADaM can not be included).

The difference tool can be accessed from here while the history tool can be accessed here. Both pages contain instructions on how to use the tools.

Back to the terminology. In the latest release (SDTM & COA) there are:

  • 24 new code lists
    • C120521 Anti-Viral Outcome of Treatment
    • C120522 Holter ECG Results
    • C120523 Holter ECG Test Code
    • C120524 Holter ECG Test Name
    • C120525 Immunogenicity Specimen Assessments Test Code
    • C120526 Immunogenicity Specimen Assessments Test Name
    • C120527 Microbiology Test Code
    • C120528 Microbiology Test Name
    • C120978 QS-Chronic Respiratory Questionnaire Self-Administered Standardized Format First Administration Version Test Name
    • C120979 QS-Chronic Respiratory Questionnaire Self-Administered Standardized Format First Administration Version Test Code
    • C120980 QS-Chronic Respiratory Questionnaire Self-Administered Standardized Format Follow-Up Administration Version Test Name
    • C120981 QS-Chronic Respiratory Questionnaire Self-Administered Standardized Format Follow-Up Administration Version Test Code
    • C120982 FT-Brief Assessment of Cognition in Schizophrenia Test Name
    • C120983 FT-Brief Assessment of Cognition in Schizophrenia Test Code
    • C120984 CC-Acute Physiology and Chronic Health Evaluation II Clinical Classificationn Test Name
    • C120985 CC-Acute Physiology and Chronic Health Evaluation II Clinical Classification Test Code
    • C120986 CC-The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index Clinical Classificationn Test Name
    • C120987 CC-The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index Clinical Classification Test Code
    • C120988 CC-Child-Pugh Clinical Test Name
    • C120989 CC-Child-Pugh Clinical Classification Test Code
    • C120990 CC-Model for End Stage Liver Disease Clinical Classificationn Test Name
    • C120991 CC-Model for End Stage Liver Disease Clinical Classification Test Code
    • C120992 CC-Negative Symptom Assessment-16 Clinical Classificationn Test Name
    • C120993 CC-Negative Symptom Assessment-16 Clinical Classification Test Code
  • 8 updated code lists and 52 updated items
    • A sizeable list. Go direct the the latest changes here and select “Update” in the right-most column. This will filter the display to show all of the updated code lists and items.
  • 9 submission values changes
    • Go direct the the difference tool here and enter “==” in the filter box in the “Submission Value” column. This will filter the display to show all of the updated submission values. This will allow the changes to be seen in context.
  • 6 deleted code lists
    • C100145 QS-Parkinson’s Disease Quality of Life Test Name
    • C100146 QS-Parkinson’s Disease Quality of Life Test Code
    • C101830 QS-Young Mania Rating Scale Test Code
    • C101831 QS-Young Mania Rating Scale Test Name
    • C103486 QS-Short Opiate Withdrawal Scale Questionnaire Test Name
    • C103487 QS-Short Opiate Withdrawal Scale Questionnaire Test Code

One thing I noticed when assembling the above lists for this blog is that there are a couple of typos “Classificationn” in four of the code list titles (C120984, C120986, C120990, C120992).

One final aspect I looked at with this release is the number of code lists and associated items that have been within the various releases. I went back to the first release in the archive (20th April 2007) and extracted the various counts in all the releases since (again, just the SDTM and COA sets). Back in the first release in 2007 we had 34 code lists and 969 items. This has since expanded to 438 code lists and 15732 items with an acceleration in the rate of production since late 2011.

The number of code lists within the CDISC terminology since April 2007

The number of code lists within the CDISC terminology since April 2007

The number of code list items within the CDISC terminology since April 2007

The number of code list items within the CDISC terminology since April 2007

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